References

smjournal

Спортивная медицина: наука и практика

Sports medicine: research and practice

2223-25242587-9014

NEICON

10.17238/ISSN2223-2524.2019.4.33

smjournal-179

Research Article

БИОМЕДИЦИНСКИЕ ТЕХНОЛОГИИ

BIOMEDICAL TECHNOLOGIES

Современные аспекты применения плазмы, обогащенной растворимыми факторами тромбоцитов, в лечении травм и заболеваний опорно-двигательного аппарата

Modern aspects of the use of plasma enriched in soluble platelet factors in the treatment of injuries and diseases of the musculoskeletal system

https://orcid.org/0000-0001-7705-9383

Потапнев

М. П.

Potapnev

M. P.

Потапнев Михаил Петрович, заведующий отделом клеточных биотехнологий, проф., д.м.н.

Минск

+375-29-638-02-71

Michael P. Potapnev, M.D., D.Sc. (Medicine), Prof., Head of the Department of Cellular BioTechnologies

Minsk

+375-29-638-02-71

mpotapnev@yandex.by

https://orcid.org/0000-0002-9930-253X

Загородный

Г. М.

Zagorodny

G. M.

Загородный Геннадий Михайлович, заместитель директора по клинике, доцент, к.м.н.

Минск

Gennady M. Zagorodny, M.D., Ph.D. (Medicine), Deputy Director for Clinic

Minsk

https://orcid.org/0000-0002-6813-4465

Кривенко

С. И.

Krivenko

S. I.

Кривенко Светлана Ивановна, заместитель директора по научной работе, доцент, д.м.н.

Минск

Svetlana I. Krivenko, M.D., D.Sc. (Medicine), Deputy Director for Research

Minsk

https://orcid.org/0000-0001-7849-6497

Богдан

В. Г.

Bogdan

V. G.

Богдан Василий Генрихович, начальник военно-медицинского факультета, проф., д.м.н.

Минск

Vasiliy G. Bogdan, M.D., D.Sc. (Medicine), Prof., Head of the Faculty of Military Medicine

Minsk

https://orcid.org/0000-0002-7691-5464

Свирский

А. О.

Svirsky

A. O.

Свирский Антон Олегович, научный сотрудник

Минск

Anton O. Svirsky, Scientist

Minsk

https://orcid.org/0000-0003-0814-8707

Ясюкевич

А. C.

Yasyukevich

A. S.

Ясюкевич Андрей Сергеевич, научный сотрудник

Минск

Andrei S. Yasyukevich, Scientist

Minsk

https://orcid.org/0000-0002-2257-6452

Асаевич

В. И.

Asaevich

V. I.

Асаевич Вадим Игоревич, младший научный сотрудник

Минск

Vadim I. Asaevich, Junior Researcher

Minsk

https://orcid.org/0000-0001-6076-3761

Букач

Д. В.

Bukach

D. V.

Букач Дмитрий Вячеславович, научный сотрудник

Минск

Dmitry V. Bukach, M.D., Scientist

Minsk

https://orcid.org/0000-0002-1002-4132

Эйсмонт

О. Л.

Eismont

O. L.

Эйсмонт Олег Леонидович, заместитель директора по научной работе, доцент, д.м.н.

Минск

Oleg L. Eismont, M.D., D.Sc. (Medicine), Deputy Director for Research

Minsk

Республиканский научно-практический центр трансфузиологии и медицинских биотехнологийБеларусьRepublican Scientific and Practical Center of Transfusiology and Medical BiotechnologiesBelarus

Республиканский научно-практический центр спортаБеларусьRepublican Scientific and Practical Center of sportsBelarus

Минский научно-практический центр хирургии, трансплантологии и гематологииБеларусьMinsk Scientific and Practical Center for Surgery, Transplantation and HematologyBelarus

Белорусский государственный медицинский университетБеларусьBelarusian State Medical UniversityBelarus

Республиканский научно-практический центр трансфузиологии и медицинских биотехнологийБеларусьRepublican Scientific and Practical Center of sportsBelarus

Республиканский научно-практический центр травматологии и ортопедииБеларусьRepublican Scientific and Practical Center of Traumatology and OrthopedicsBelarus

2019

28082020

943345

2020

Потапнев М.П., Загородный Г.М., Кривенко С.И., Богдан В.Г., Свирский А.О., Ясюкевич А.C., Асаевич В.И., Букач Д.В., Эйсмонт О.Л.

Potapnev M.P., Zagorodny G.M., Krivenko S.I., Bogdan V.G., Svirsky A.O., Yasyukevich A.S., Asaevich V.I., Bukach D.V., Eismont O.L.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.smjournal.ru/jour/article/view/179

В обзоре литературы представлены данные о новом направлении в лечении спортивных травма и заболеваний опорно-двигательного аппарата – использовании собственной плазмы, обогащенной тромбоцитами плазмы, обогащенной растворимыми факторами тромбоцитов (PRP/ПОРФТ). PRP/ПОРФТ оказывает противовоспалительное, обезболивающее, антикатаболическое и регенеративное действие при локальном введении в область поражения. Рассмотрены вопросы технологий приготовления и клинического применения PRP/ПОРФТ. Дан анализ результатов клинических наблюдений по её использованию в спортивной медицине и повреждениях опорно-двигательного аппарата. Показана клиническая эффективность 2-3 кратного введения PRP/ПОРФТ в область травмы или повреждения мышц, связок, суставов. Наиболее эффективно было использование PRP/ПОРФТ при лечении эпикондилита локтевого сустава и остеоартрита. Не выявлено достоверной эффективности применения PRP/ПОРФТ при повреждениях ахиллова сухожилия. Отмечен наибольший клинический эффект применения PRP/ПОРФТ при травмах и заболеваниях опорно-двигательного аппарата на начальных этапах лечения, а также при проведении реабилитационных курсов терапии.

The review of literature presents the new direction in the treatment of sports injuries and diseases of the musculoskeletal system – using of autologous platelet-rich plasma/plasma enriched in soluble platelet factors (PRP/PORFT). PRP/PORFT reveals anti-inflammatory, analgesic, anticatabolic and regenerative effects after local injection to affected area. Technology of preparation and clinical application of PRP/PORFT were under consideration. There were described the results of clinical studies on PRP/PORFT application in sports medicine and damage of musculoskeletal system. It was shown the clinical efficacy of 2-3 injections of PRP/PORFT into the area of muscle, ligaments, joints injury. Most effective use of PRP/PORFT was shown for therapy of lateral epicondylitis and osteoarthritis. There were no yet evidences for its efficacy in therapy of patients with damaged Achilles tendon. The best clinical effects of PRP/PORFT use was demonstrated in patients with trauma and damage of musculoskeletal system at the initial stages of treatment, and also as a part of rehabilitation courses.

плазмаобогащенная тромбоцитами/плазмаобогащенная растворимыми факторами тромбоцитовспортивные травмызаболеванияопорно-двигательный аппарат

platelet-rich plasma/plasma enriched in soluble platelet factorssports injurydiseasemusculoskeletal system

Работа выполнена в рамках выполнения НИОК(Т)Р (гранты Министерства здравоохранения Республики Беларусь № 20191216 и 20192193)

This study was conducted with financial support of Ministry of Health the Republic of Belarus (grants # 20191216 and # 20192193).

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The authors declare that there are no conflicts of interest present.