smjournalСпортивная медицина: наука и практикаSports medicine: research and practice2223-25242587-9014NEICON10.47529/2223-2524.2021.4.8smjournal-348Research ArticleСПОРТИВНОЕ ПИТАНИЕSPORTS SUPPLEMENTSО применении глютамин-содержащих продуктов специализированного питания в спортеOn the use of glutamine-containing specialty foods in sportshttps://orcid.org/0000-0003-2107-6525СливинА. В.SlivinA. V.

Сливин Антон Вячеславович, врач-ординатор кафедры реабилитации, спортивной медицины и физической культуры педиатрического факультета

117513, Россия, Москва, ул. Островитянова, 1, стр. 6

Anton V. Slivin, resident physician of Rehabilitation and Sports Medicine Department

1, bldg. 6, Ostrovityanova str., Moscow, 117513, Russia

https://orcid.org/0000-0002-3807-3286ЕфимовП. В.EfimovP. V.

Ефимов Павел Владимирович, врач-ординатор кафедры реабилитации, спортивной медицины и физической культуры педиатрического факультета

117513, Россия, Москва, ул. Островитянова, 1, стр. 6

Pavel V. Efimov, resident physician of Rehabilitation and Sports Medicine Department

1, bldg. 6, Ostrovityanova str., Moscow, 117513, Russia

https://orcid.org/0000-0003-2062-0592ЗоренкоА. В.ZorenkoA. V.

Зоренко Алла Владимировна, врач по спортивной медицине

121059, Россия, Москва, ул. Б. Дорогомиловская, 5

Alla V. Zorenko, sports medicine physician

5, B. Dorogomilovskaya str., Moscow, 121059, Russia

https://orcid.org/0000-0001-5358-2313КупеевМ. В.KupeevM. V.

Купеев Марат Валериевич, врач по спортивной медицине

121059, Россия, Москва, ул. Б. Дорогомиловская, 5

Marat V. Kupeev, sports medicine physician

5, B. Dorogomilovskaya str., Moscow, 121059, Russia

https://orcid.org/0000-0002-6015-4947ЯшинТ. А.YashinT. A.

Яшин Тимофей Александрович, заведующий кабинетом коррекции функционального состояния спортсменов

121059, Россия, Москва, ул. Б. Дорогомиловская, 5

Timofey A. Yashin, head of the office for the correction of the functional state of athletes

5, B. Dorogomilovskaya str., Moscow, 121059, Russia

https://orcid.org/0000-0003-3792-1682ЯдгаровМ. Я.YadgarovM. Y.

Ядгаров Михаил Яковлевич, младший научный сотрудник

121059, Россия, Москва, ул. Б. Дорогомиловская, 5

Mikhail Y. Yadgarov, junior researcher

5, B. Dorogomilovskaya str., Moscow, 121059, Russia

https://orcid.org/0000-0001-5504-8122БазановичС. А.BazanovichS. A.

Базанович Сергей Александрович, врач-кибернетик

121059, Россия, Москва, ул. Б. Дорогомиловская, 5

Sergey A. Bazanovich, cybernetic physician

5, B. Dorogomilovskaya str., Moscow, 121059, Russia

https://orcid.org/0000-0002-0474-7000ФилипповаН. С.PhilippovaN. S.

Филиппова Наталья Сергеевна, медицинская сестра по массажу

121059, Россия, Москва, ул. Б. Дорогомиловская, 5

Natalia S. Philippova, massage nurse

5, B. Dorogomilovskaya str., Moscow, 121059, Russia

https://orcid.org/0000-0002-2281-9936ПарастаевС. А.ParastaevS. A.

Парастаев Сергей Андреевич, профессор, д.м.н., ведущий научный сотрудник; профессор кафедры реабилитации, спортивной медицины и физической культуры педиатрического факультета

121059, Россия, Москва, ул. Б. Дорогомиловская, 5

117513, Россия, Москва, ул. Островитянова, 1, стр. 6

Sergey A. Parastaev, M.D., D.Sc. (Medicine), Leading Researcher; Professor of the Rehabilitation and Sports Medicine Department

5, B. Dorogomilovskaya str., Moscow, 121059, Russia

1, bldg. 6, Ostrovityanova str., Moscow, 117513, Russia

ФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н. И. Пирогова» Минздрава РоссииРоссияPirogov Russian National Research Medical UniversityRussian FederationФГБУ «Федеральный научно-клинический центр спортивной медицины и реабилитации Федерального медико-биологического агентства»РоссияFederal Research and Clinical Center of Sports Medicine and Rehabilitation of Federal Medical Biological AgencyRussian FederationФГБУ «Федеральный научно-клинический центр спортивной медицины и реабилитации Федерального медико-биологического агентства»; ФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н. И. Пирогова» Минздрава РоссииРоссияFederal Research and Clinical Center of Sports Medicine and Rehabilitation of Federal Medical Biological Agency; Pirogov Russian National Research Medical UniversityRussian Federation2021060520221145768Copyright © Сливин А.В., Ефимов П.В., Зоренко А.В., Купеев М.В., Яшин Т.А., Ядгаров М.Я., Базанович С.А., Филиппова Н.С., Парастаев С.А., 20222022Сливин А.В., Ефимов П.В., Зоренко А.В., Купеев М.В., Яшин Т.А., Ядгаров М.Я., Базанович С.А., Филиппова Н.С., Парастаев С.А.Slivin A.V., Efimov P.V., Zorenko A.V., Kupeev M.V., Yashin T.A., Yadgarov M.Y., Bazanovich S.A., Philippova N.S., Parastaev S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.smjournal.ru/jour/article/view/348

Глютамин (ГЛН) и глютаминовая кислота (ГЛК) вовлечены во множество метаболических процессов — от синтеза нуклеотидов до проведения нервных импульсов; также ГЛН является энергетическим субстратом для ИКК, что делает его важным звеном в реализации иммунного ответа. В стрессовых ситуациях, к которым относится значительная физическая нагрузка, уровень ГЛН и ГЛК в плазме снижается в результате активного расхода аминокислоты во многих биохимических реакциях. Дефицит ГЛН может привести к ряду негативных проявлений у спортсменов и отрицательно сказаться на спортивной результативности. Изучение эффектов глютаминовой недостаточности и возможного восполнения дефицита потреблением экзогенных форм субстанции при применении глютамин­содержащих продуктов явилось целью данной работы; особое внимание было уделено исследованию транзиторного снижения иммунной функции как актуальному фактору, нарушающему режим спортивной подготовки.

Glutamine (GLN) and glutamic acid (GLA) are involved in many metabolic processes, from nucleotide synthesis to nerve impulse conduction; GLN is also an energy substrate for immunocompetent cells, making it an important link in the immune response. In stressful situations, which include significant physical activity, plasma levels of GLN and GLA decrease as a result of the amino acid being actively consumed in many biochemical reactions. GLN deficiency can lead to a number of negative manifestations in athletes and adversely affect athletic performance. The purpose of this work was to study the effects of glutamine deficiency and the possible replenishment of the deficiency by the consumption of exogenous forms of the substance when using glutamine-containing products; special attention was paid to the study of transient decrease in immune function as a relevant factor that impairs the mode of sports training.

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The authors declare that there are no conflicts of interest present.