smjournalСпортивная медицина: наука и практикаSports medicine: research and practice2223-25242587-9014NEICON10.47529/2223-2524.2022.2.2smjournal-408Research ArticleСПОРТИВНОЕ ПИТАНИЕSPORTS SUPPLEMENTSВлияние микронутриентов на показатели зрительных функций у спортсменов: ретроспективный анализ актуальных статейThe impact of micronutrients on athletes’ vision: a retrospective analysis of revalent articleshttps://orcid.org/0000-0002-8111-0919МедведевИ. Б.MedvedevI. B.

Медведев Игорь Борисович, доктор медицинских наук, кафедра офтальмологии ФДПО

SPIN-код: 5779-2406

117997, г. Москва, ул. Островитянова, 1

Igor B. Medvedev, M.D., Ph.D. (Medicine), Department of Ophthalmology

SPIN: 5779-2406

1 Ostrovityanova str., Moscow, 117997

7280033@mail.ruhttps://orcid.org/0000-0002-1453-0163АлиеваШ. А.AlievaS. A.

Алиева Ширин Алиевна, студент 6-го курса, кафедра офтальмологии ФДПО

117997, г. Москва, ул. Островитянова, 1

Shirin A. Alieva, 6th year student, Department of Ophthalmology

1 Ostrovityanova str., Moscow, 117997

shirin.aliewa@yandex.ruhttps://orcid.org/0000-0002-4447-5919ГусаковМ. В.GusakovM. V.

Гусаков Михаил Владимирович, студент 5-го курса, кафедра офтальмологии ФДПО

SPIN-код: 8949-9300

117997, г. Москва, ул. Островитянова, 1

Mikhail V. Gusakov, 5th year student, Department of Ophthalmology

SPIN: 8949-9300

1 Ostrovityanova str., Moscow, 117997

gmiklv@gmail.comhttps://orcid.org/0000-0002-9190-4632МедведеваН. И.MedvedevaN. I.

Медведева Наталья Игоревна, кандидат медицинских наук, ассистент, кафедра реабилитации, спортивной медицины и физической культуры педиатрического факультета

SPIN-код: 1949-5793

117997, г. Москва, ул. Островитянова, 1

Natalya I. Medvedeva, Ph.D. (Medicine), Assistant, Department of Sports Medicine and Physical Culture, Faculty of pediatrics

SPIN: 1949-5793

1 Ostrovityanova str., Moscow, 117997

smirnula@yandex.ruhttps://orcid.org/0000-0003-3441-9072ДергачёваН. Н.DergachevaN. N.

Дергачева Надежда Николаевна, ассистент, кафедра офтальмологии ФДПО

SPIN-код: 4932-0400

117997, г. Москва, ул. Островитянова, 1

Nadezhda N. Dergacheva, Assistant, Department of Ophthalmology

SPIN: 4932-0400

1 Ostrovityanova str., Moscow, 117997

deb20052005@yandex.ruФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава РоссииРоссияPirogov Russian National Research Medical UniversityRussian Federation2022251020221226066Copyright © Медведев И.Б., Алиева Ш.А., Гусаков М.В., Медведева Н.И., Дергачёва Н.Н., 20222022Медведев И.Б., Алиева Ш.А., Гусаков М.В., Медведева Н.И., Дергачёва Н.Н.Medvedev I.B., Alieva S.A., Gusakov M.V., Medvedeva N.I., Dergacheva N.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.smjournal.ru/jour/article/view/408

Глаза, как и другие органы человека, испытывают существенный дефицит питательных веществ при чрезмерных нагрузках, что может резко отразиться на показателях зрительных функций и, соответственно, качестве жизни и тренировок спортсмена.

В данной статье определена зависимость между состоянием органа зрения и спортивными результатами. Также представлен обзор последних научных исследований, касающихся влияния биологически значимых микронутриентов на функции зрительного анализатора, с примерами продуктов, способствующих улучшению зрительных функций.

The eyes, like other human organs, are deficient in nutrients during over-training, which can affect visual acuity and, accordingly, the quality of training.

This article defines the importance of the organ of vision for sports results. It also provides an overview of the latest scientific research on the impact of biologically significant micronutrients on the functions of the visual analyzer with examples of products that help improve visual functions.

орган зренияострота зрениявитаминымикронутриентыкаротиноидыспортсменыorgan of visionvisual acuitynutrientsvitaminscarotenoidsathletesReferencesLim J. C., Arredondo M. C., Braakhuis J. A., Donaldson P.J. Vitamin C and the Lens: New Insights into Delaying the Onset of Cataract. Nutrients. 2020;12(10):31–42. https://doi.org/10.3390/nu12103142Lim J. C., Arredondo M. C., Braakhuis J. A., Donaldson P.J. Vitamin C and the Lens: New Insights into Delaying the Onset of Cataract. Nutrients. 2020;12(10):31–42. https://doi.org/10.3390/nu12103142Koppenol W.H. Hider R.H. Iron and Redox Cycling. Do’s and Don’ts. Free Radic. Biol. Med. 2019;133:3–10. https://doi.org/10.1016/j.freeradbiomed.2018.09.022Koppenol W.H. Hider R.H. Iron and Redox Cycling. Do’s and Don’ts. Free Radic. Biol. Med. 2019;133:3–10. https://doi.org/10.1016/j.freeradbiomed.2018.09.022Tanito M. Reported evidence of vitamin E protection against cataract and glaucoma. Free Radic. Biol. Med. 2021;177(12):100–119. https://doi.org/10.1016/j.freeradbiomed.2021.10.027.Tanito M. Reported evidence of vitamin E protection against cataract and glaucoma. Free Radic. Biol. Med. 2021;177(12):100–119. https://doi.org/10.1016/j.freeradbiomed.2021.10.027.McNeil J. J., Robman L. G., Tikellis M.I., Sinclair C.A. Vitamin E supplementation and cataract. Ophthalmology. 2004;111(1):75–84. https://doi.org/10.1016/j.ophtha.2003.04.009McNeil J. J., Robman L. G., Tikellis M.I., Sinclair C.A. Vitamin E supplementation and cataract. Ophthalmology. 2004;111(1):75–84. https://doi.org/10.1016/j.ophtha.2003.04.009Pellegrini M., Senni C., Bernabei F., Cicero A.F.G., Vagge A. The Role of Nutrition and Nutritional Supplements in Ocular Surface Diseases. Nutrients. 2020;12(4): 952. https://doi.org/10.3390/nu12040952Pellegrini M., Senni C., Bernabei F., Cicero A.F.G., Vagge A. The Role of Nutrition and Nutritional Supplements in Ocular Surface Diseases. Nutrients. 2020;12(4): 952. https://doi.org/10.3390/nu12040952Hou Y.-C., Huang J.-Y., Yeh P.-T. A randomized, doubleblind, placebo-controlled study of oral antioxidant supplement therapy in patients with dry eye syndrome. Clin. Ophthalmol. 2016;10:813–820. https://doi.org/10.2147/OPTH.S106455Hou Y.-C., Huang J.-Y., Yeh P.-T. A randomized, doubleblind, placebo-controlled study of oral antioxidant supplement therapy in patients with dry eye syndrome. Clin. Ophthalmol. 2016;10:813–820. https://doi.org/10.2147/OPTH.S106455Jin K.W., Ro J.W., Shin Y.J., Hyon J.Y., Wee W.R. Correlation of vitamin D levels with tear film stability and secretion in patients with dry eye syndrome. Acta Ophthalmol. 2016;95(3):230–235. https://doi.org/10.1111/aos.13241Jin K.W., Ro J.W., Shin Y.J., Hyon J.Y., Wee W.R. Correlation of vitamin D levels with tear film stability and secretion in patients with dry eye syndrome. Acta Ophthalmol. 2016;95(3):230–235. https://doi.org/10.1111/aos.13241Yang C.-H., Albietz J., Harkin D.G., Kimlin M.G., Schmid K.L. Impact of oral vitamin D supplementation on the ocular surface in people with dry eye and/or low serum vitamin D. Cont. Lens Anterior Eye. 2017;41(1):69–76. https://doi.org/10.1016/j.clae.2017.09.007Yang C.-H., Albietz J., Harkin D.G., Kimlin M.G., Schmid K.L. Impact of oral vitamin D supplementation on the ocular surface in people with dry eye and/or low serum vitamin D. Cont. Lens Anterior Eye. 2017;41(1):69–76. https://doi.org/10.1016/j.clae.2017.09.007Hwang J.S., Hwang J.S., Lee Y.P., Shin Y.J. Vitamin D Enhances the Efficacy of Topical Artificial Tears in Patients with Dry Eye Disease. Cornea. 2019;38(3):304–310. https://doi.org/10.1097/ICO.0000000000001822Hwang J.S., Hwang J.S., Lee Y.P., Shin Y.J. Vitamin D Enhances the Efficacy of Topical Artificial Tears in Patients with Dry Eye Disease. Cornea. 2019;38(3):304–310. https://doi.org/10.1097/ICO.0000000000001822Tei M., Spurr-Michaud S.J., Tisdale A.S., Gipson I.K. Vitamin A deficiency alters the expression of mucin genes by the rat ocular surface epithelium. Invest. Ophthalmol. Vis. Sci. 2000;41(1):82–88.Tei M., Spurr-Michaud S.J., Tisdale A.S., Gipson I.K. Vitamin A deficiency alters the expression of mucin genes by the rat ocular surface epithelium. Invest. Ophthalmol. Vis. Sci. 2000;41(1):82–88.Spits Y., De Laey J.-J., Leroy B.P. Rapid recovery of night blindness due to obesity surgery after vitamin A repletion therapy. Br. J. Ophthalmol. 2004;88(4):583–585. https://doi.org/10.1136/bjo.2003.022459Spits Y., De Laey J.-J., Leroy B.P. Rapid recovery of night blindness due to obesity surgery after vitamin A repletion therapy. Br. J. Ophthalmol. 2004;88(4):583–585. https://doi.org/10.1136/bjo.2003.022459Lee W.B., Hamilton S.M., Harris J.P., Schwab I.R. Ocular Complications of Hypovitaminosis A after Bariatric Surgery. Ophthalmology. 2005;112(6):1031–1034. https://doi.org/10.1016/j.ophtha.2004.12.045Lee W.B., Hamilton S.M., Harris J.P., Schwab I.R. Ocular Complications of Hypovitaminosis A after Bariatric Surgery. Ophthalmology. 2005;112(6):1031–1034. https://doi.org/10.1016/j.ophtha.2004.12.045Tseng S.C., Maumenee A.E., Stark W.J., Maumenee I.H., Jensen A.D., Green W.R., Kenyon K.R. Topical Retinoid Treatment for Various Dry-eye Disorders. Ophthalmology. 1985;92(6):717–727. https://doi.org/10.1016/s0161-6420(85)33968-4Tseng S.C., Maumenee A.E., Stark W.J., Maumenee I.H., Jensen A.D., Green W.R., Kenyon K.R. Topical Retinoid Treatment for Various Dry-eye Disorders. Ophthalmology. 1985;92(6):717–727. https://doi.org/10.1016/s0161-6420(85)33968-4Ohashi Y., Watanabe H., Kinoshita S., Hosotani H., Umemoto M. Vitamin A Eyedrops for Superior Limbic Keratoconjunctivitis. Am. J. Ophthalmol. 1988;105(5):523–527. https://doi.org/10.1016/0002-9394(88)90245-0Ohashi Y., Watanabe H., Kinoshita S., Hosotani H., Umemoto M. Vitamin A Eyedrops for Superior Limbic Keratoconjunctivitis. Am. J. Ophthalmol. 1988;105(5):523–527. https://doi.org/10.1016/0002-9394(88)90245-0Alanazi S.A., El-Hiti G.A., Al-Baloud A.A., Alfarhan M.I., Al-Shahrani A. Effects of short-term oral vitamin A supplementation on the ocular tear film in patients with dry eye. Сlinical Ophthalmology. 2019;13:599–604. https://doi.org/10.2147/OPTH.S198349Alanazi S.A., El-Hiti G.A., Al-Baloud A.A., Alfarhan M.I., Al-Shahrani A. Effects of short-term oral vitamin A supplementation on the ocular tear film in patients with dry eye. Сlinical Ophthalmology. 2019;13:599–604. https://doi.org/10.2147/OPTH.S198349Richer P. S., Stiles W., Graham-Hoffman K., Levin M., Ruskin D. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration. Optometry. 2011;82(11):667–680. https://doi.org/10.1016/j.optm.2011.08.008Richer P. S., Stiles W., Graham-Hoffman K., Levin M., Ruskin D. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration. Optometry. 2011;82(11):667–680. https://doi.org/10.1016/j.optm.2011.08.008Richer S., Park D.-W., Epstein R., Wrobel J. S., Thomas C. Macular Re-pigmentation Enhances Driving Vision in Elderly Adult Males with Macular Degeneration. Clin. Exp. Ophthalmol. 2012;3(3):217–222. https://doi.org/10.4172/2155-9570.1000217Richer S., Park D.-W., Epstein R., Wrobel J. S., Thomas C. Macular Re-pigmentation Enhances Driving Vision in Elderly Adult Males with Macular Degeneration. Clin. Exp. Ophthalmol. 2012;3(3):217–222. https://doi.org/10.4172/2155-9570.1000217Stringham J.M., Stringham N.T., O’Brien K. J. Macular Carotenoid Supplementation Improves Visual Performance, Sleep Quality, and Adverse Physical Symptoms in Those with High Screen Time Exposure. Foods. 2017;6(7):47. https://doi.org/10.3390/foods6070047Stringham J.M., Stringham N.T., O’Brien K. J. Macular Carotenoid Supplementation Improves Visual Performance, Sleep Quality, and Adverse Physical Symptoms in Those with High Screen Time Exposure. Foods. 2017;6(7):47. https://doi.org/10.3390/foods6070047Parisi V., Tedeschi M., Gallinaro G., Varano M., Saviano S. Carotenoids and antioxidants in age-related maculopathy italian study: multifocal electroretinogram modifications after 1 year. Ophthalmology. 2008;115(2):324–333. https://doi.org/10.1016/j.ophtha.2007.05.029Parisi V., Tedeschi M., Gallinaro G., Varano M., Saviano S. Carotenoids and antioxidants in age-related maculopathy italian study: multifocal electroretinogram modifications after 1 year. Ophthalmology. 2008;115(2):324–333. https://doi.org/10.1016/j.ophtha.2007.05.029Stringham J.M., Stringham N.T. Serum and retinal responses to three different doses of macular carotenoids over 12 weeks of supplementation. Exp. eye res. 2016;151:1–8. https://doi.org/10.1016/j.exer.2016.07.005Stringham J.M., Stringham N.T. Serum and retinal responses to three different doses of macular carotenoids over 12 weeks of supplementation. Exp. eye res. 2016;151:1–8. https://doi.org/10.1016/j.exer.2016.07.005Dawczynski J., Jentsch S., Schweitzer D., Hammer M., Lang G. E., Strobel J. Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study. Graefe’s arch. clin. exp. ophthalmol. 2013;251(12):2711–2723. https://doi.org/10.1007/s00417-013-2376-6Dawczynski J., Jentsch S., Schweitzer D., Hammer M., Lang G. E., Strobel J. Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study. Graefe’s arch. clin. exp. ophthalmol. 2013;251(12):2711–2723. https://doi.org/10.1007/s00417-013-2376-6Huang Y.-M., Dou H.-L., Huang F.-F., Xu X.-R., Zou Z.-Y. Effect of supplemental lutein and zeaxanthin on serum, macular pigmentation, and visual performance in patients with early age-related macular degeneration. Biomed. Res. Int.. 2015;2015: 564738. https://doi.org/10.1155/2015/564738Huang Y.-M., Dou H.-L., Huang F.-F., Xu X.-R., Zou Z.-Y. Effect of supplemental lutein and zeaxanthin on serum, macular pigmentation, and visual performance in patients with early age-related macular degeneration. Biomed. Res. Int.. 2015;2015: 564738. https://doi.org/10.1155/2015/564738Serhan C.N. Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation. Am. J. Ophthal. 2010;177(4):1576–1591. https://doi.org/10.2353/ajpath.2010.100322Serhan C.N. Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation. Am. J. Ophthal. 2010;177(4):1576–1591. https://doi.org/10.2353/ajpath.2010.100322Gronert K., Maheshwari N., Khan N., Hassan I.R., Dunn M. A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense. J. biol. chem. 2005;280(15):15267–15278. https://doi.org/10.1074/jbc.M410638200Gronert K., Maheshwari N., Khan N., Hassan I.R., Dunn M. A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense. J. biol. chem. 2005;280(15):15267–15278. https://doi.org/10.1074/jbc.M410638200Liu Y., Kam W.R., Sullivan D.A. Influence of Omega 3 and 6 Fatty Acids on Human Meibomian Gland Epithelial Cells. Cornea. 2016;35(8):1122–1126. https://doi.org/10.1097/ICO.0000000000000874Liu Y., Kam W.R., Sullivan D.A. Influence of Omega 3 and 6 Fatty Acids on Human Meibomian Gland Epithelial Cells. Cornea. 2016;35(8):1122–1126. https://doi.org/10.1097/ICO.0000000000000874Rashid S., Jin Y., Ecoiffier T., Barabino S., Schaumberg D.A. Topical Omega-3 and Omega-6 Fatty Acids for Treatment of Dry Eye. Arch. ophthalmol. 2008;126(2):219–225. https://doi.org/10.1001/archophthalmol.2007.61Rashid S., Jin Y., Ecoiffier T., Barabino S., Schaumberg D.A. Topical Omega-3 and Omega-6 Fatty Acids for Treatment of Dry Eye. Arch. ophthalmol. 2008;126(2):219–225. https://doi.org/10.1001/archophthalmol.2007.61Mudgil P. Evaluation of use of essential fatty acids in topical ophthalmic preparations for dry eye. The ocular surface. 2020; 18:74-79. https://doi.org/10.1016/j.jtos.2019.10.001.Mudgil P. Evaluation of use of essential fatty acids in topical ophthalmic preparations for dry eye. The ocular surface. 2020; 18:74-79. https://doi.org/10.1016/j.jtos.2019.10.001.Downie L.E., Hom M.M., Berdy G.J., El-Harazi S., Verachtert A. An artificial tear containing flaxseed oil for treating dry eye disease: A randomized controlled trial. Ocul. Surf. 2020;18(1)148–157. https://doi.org/10.1016/j.jtos.2019.11.004Downie L.E., Hom M.M., Berdy G.J., El-Harazi S., Verachtert A. An artificial tear containing flaxseed oil for treating dry eye disease: A randomized controlled trial. Ocul. Surf. 2020;18(1)148–157. https://doi.org/10.1016/j.jtos.2019.11.004Borovanský J. Zinc in pigmented cells and structures, interactions and possible roles. Sborník lékar̆ský. 1994;95(4): 309–320.Borovanský J. Zinc in pigmented cells and structures, interactions and possible roles. Sborník lékar̆ský. 1994;95(4): 309–320.Fletcher A.E. Free radicals, antioxidants and eye diseases: evidence from epidemiological studies on cataract and agerelated macular degeneration. Ophthalmic Res. 2010;44(3):191–198. https://doi.org/10.1159/000316476Fletcher A.E. Free radicals, antioxidants and eye diseases: evidence from epidemiological studies on cataract and agerelated macular degeneration. Ophthalmic Res. 2010;44(3):191–198. https://doi.org/10.1159/000316476Albanes D., Heinonen O.P., Huttunen J.K., Taylor P.R., Virtamo J. Effects of alpha-tocopherol and beta-carotene supplements on cancer incidence in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study. Am. J. Clin. Nutr. 1995;62(6 Suppl):1427–1430. https://doi.org/10.1093/ajcn/62.6.1427SAlbanes D., Heinonen O.P., Huttunen J.K., Taylor P.R., Virtamo J. Effects of alpha-tocopherol and beta-carotene supplements on cancer incidence in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study. Am. J. Clin. Nutr. 1995;62(6 Suppl):1427–1430. https://doi.org/10.1093/ajcn/62.6.1427SOmenn G.S., Thornquist M.D., Balmes J., Cullen M.R., Glass A. Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J. Natl. Cancer Inste. 1996;88(21):1550–1559. https://doi.org/10.1093/jnci/88.21.1550Omenn G.S., Thornquist M.D., Balmes J., Cullen M.R., Glass A. Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J. Natl. Cancer Inste. 1996;88(21):1550–1559. https://doi.org/10.1093/jnci/88.21.1550Скурихин И.М., Тутельян В.А., ред. Химический состав российских пищевых продуктов: справочник. Москва: ДеЛи принт; 2002.Skurikhina I.M., Tutel’yana V.A., eds. Chemical composition of Russian food products: a reference book. Moscow: DeLiprint Publ.; 2002 (In Russ.).

The authors declare that there are no conflicts of interest present.