smjournalСпортивная медицина: наука и практикаSports medicine: research and practice2223-25242587-9014NEICON10.47529/2223-2524.2024.3.4smjournal-659Research ArticleФИЗИОЛОГИЯ И БИОХИМИЯ СПОРТАSPORTS PHYSIOLOGY AND BIOCHEMISTRYДинамика маркера повреждения миокарда тропонина Т у биатлонистов высокого класса на этапах подготовительного периодаDynamics of the myocardial damage marker troponin T in elite biathlonists at the stages of the early seasonhttps://orcid.org/0000-0002-5945-0722ДикунецМ. А.DikunetsM. A.

Дикунец Марина Александровна, кандидат химических наук, ведущий научный сотрудник лаборатории биохимии

105005, Москва, Елизаветинский переулок, 10с1.

Marina A. Dikunets, Ph.D. (Chemistry), Leading Researcher, Laboratory of Biochemistry

10c1 Elizavetinsky lane, Moscow, 105005

dikunets.m.a@vniifk.ruhttps://orcid.org/0000-0002-3725-5651ФедотоваЕ. В.FedotovaE. V.

Федотова Елена Викторовна, доктор педагогических наук, доцент, ведущий научный сотрудник лаборатории биохимии

105005, Москва, Елизаветинский переулок, 10с1.

Elena V. Fedotova, D.Sc. (Pedagogy), Associate Professor, Leading Researcher, Laboratory of Biochemistry

10c1 Elizavetinsky lane, Moscow, 105005

fedotova.e.v@vniifk.ruhttps://orcid.org/0000-0002-1064-3283ДудкоГ. А.DudkoG. A.

Дудко Григорий Алексеевич, старший научный сотрудник лаборатории биохимии

105005, Москва, Елизаветинский переулок, 10с1.

Grigory A. Dudko, Senior Researcher, Laboratory of Biochemistry

10c1 Elizavetinsky lane, Moscow, 105005

dudko.g.a@vniifk.ruhttps://orcid.org/0000-0001-9371-6494ВирюсЭ. Д.VirusE. D.

Вирюс Эдуард Даниэлевич, доктор химических наук, заведующий лабораторией биохимии

105005, Москва, Елизаветинский переулок, 10с1.

Edward D. Virus, D.Sc. (Chemistry), Head of the Laboratory of Biochemistry

10c1 Elizavetinsky lane, Moscow, 105005

virus.e.d@vniifk.ruФГБУ «Федеральный научный центр физической культуры и спорта»РоссияFederal Science Center of Physical Culture and SportRussian Federation2024200120251434654Copyright © Дикунец М.А., Федотова Е.В., Дудко Г.А., Вирюс Э.Д., 20252025Дикунец М.А., Федотова Е.В., Дудко Г.А., Вирюс Э.Д.Dikunets M.A., Fedotova E.V., Dudko G.A., Virus E.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.smjournal.ru/jour/article/view/659Цель исследования

Цель исследования: изучение динамики маркера повреждения миокарда тропонина Т (cardiac troponin T, cTnT) у биатлонистов высокого класса под воздействием циклических средств подготовки, используемых на этапах подготовительного периода годичного тренировочного цикла.

Методы

Методы: в исследовании приняли участие биатлонисты, проходящие централизованную подготовку в составе сборной команды Российской Федерации (n = 23). Количественное измерение cTnT в сыворотке осуществляли методом электрохемилюминесцентного анализа.

Результаты

Результаты: среднегрупповое содержание cTnT в крови биатлонистов не превышало верхней границы референтного интервала, установленного для здоровых мужчин (< 14 пг/мл). Концентрация cTnT на общеподготовительном этапе была достоверно выше, чем на специально-подготовительном (p < 0,05), статистически значимых различий между специально-подготовительным и предсоревновательным этапами не обнаружено (p > 0,05). Максимальные уровни cTnT в группе спортсменов были зафиксированы в мае и июне, в июле его концентрация снижалась на уровне тенденции (p > 0,05), а с августа по октябрь зафиксировано достоверное снижение (p < 0,05).

Заключение

Заключение: низкая тканевая специфичность АЛТ и АСТ не позволяет достоверно выявить функциональную перегрузку миокарда в ответ на физические нагрузки. Спорт сменам с аномальными концентрациями cTnT в крови с целью стратификации риска рекомендуется диагностика сердечно-сосудистой системы в рамках углубленного медико-биологического обеспечения, поскольку нельзя исключать тот факт, что регулярные повторные нагрузки, направленные на развитие выносливости, каждая из которых вызывает субклинические эффекты, могут иметь кумулятивный эффект на структуру или функцию сердца.

Aim of the study

Aim of the study: To study the quantitative dynamics of the myocardial damage marker troponin T (cTnT) in elite biathlonists as a response to the cyclic training aids used at the stages of the early season during the annual training cycle.

Methods

Methods: The study involved 23 biathlonists undergoing centralized training as members of the national team of the Russian Federation. Serum cTnT quantitation was performed by means of electrochemiluminescent assay using Elecsys Troponin T hs reagent kit (Roche Diagnostics, Germany).

Results

Results: The mean group cTnT blood level in biathlonists did not exceed the upper limit of cardiac marker reference range established for healthy men (< 14 pg/ml). cTnT concentration of at the general preliminary stage was significantly higher than at the special preliminary stage (p < 0.05), whereas statistically significant differences between the special preliminary and precompetition stages were not found (p > 0.05). The maximum cTnT levels in the group of athletes were recorded in May and June, in July its concentration decreased at the trend level (p > 0.05), then from August to October a significant decrease was documented (p < 0.05).

Conclusion

Conclusion: The low ALT and AST tissue specificity does nor reliably reveal functional myocardial overload as the response to physical exertion. In order to stratify the risk athletes with abnormal blood cTnT levels are recommended to diagnose the cardiovascular system within the in-depth biomedical observation, since it cannot be excluded that repeated bouts of endurance exercise, each causing subclinical effects, may have a cumulative effect on cardiac structure or function.

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The authors declare that there are no conflicts of interest present.