smjournalСпортивная медицина: наука и практикаSports medicine: research and practice2223-25242587-9014NEICON10.47529/2223-2524.2025.2.4smjournal-704Research ArticleФАРМАКОЛОГИЧЕСКАЯ ПОДДЕРЖКАSPORTS PHARMACOLOGYВлияние водородных ингаляций на функциональные характеристики и газовые биомаркеры кишечника у спортсменов-борцов при физической нагрузкеEffect of hydrogen inhalation on functional characteristics and intestinal gas biomarkers in wrestlers during physical exercisehttps://orcid.org/0000-0001-8942-4851МедведевО. С.MedvedevO. S.

Медведев Олег Стефанович - д.м.н., профессор, заведующий кафедрой фармакологии МНОИ, ФГБОУ ВО «МГУ им. М.В. Ломоносова»; заведующий лабораторией экспериментальной фармакологии Научно-исследовательского института экспериментальной кардиологии имени академика В.Н. Смирнова ФГБУ «НМИЦК им. акад. Е.И. Чазова» МЗ РФ.

119991, Москва, Ломоносовский проспект, д. 27, корп. 1; 121552, Москва, ул. Академика Чазова, 15а

Oleg S. Medvedev - M.D., D.Sc. (Medicine), Professor, Head of the Department of Pharmacology, Medical Scientific and Educational Institute, M.V. Lomonosov Moscow State University; Head of the Laboratory of Experimental Pharmacology, Scientific Research Institute of Experimental Cardiology named after Academician V.N. Smirnov, National Medical Research Centre of Cardiology named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation.

1 Leninskiye Gory str., Moscow, 119991; 15A Akademika Chazova str., Moscow, 121552

oleg.medvedev@gmail.comЮжаковА. А.UzhakovA. A.

Южаков Алексей Анатольевич - вице-президент.

614000, Пермь, ул. Ленина, 92

Aleksey A. Uzhakov - Vice President, Perm City Federation of Martial Arts.

92 Lenina str., Perm, 614000

metallmach@gmail.comКонноваО. Л.KonnovaO. L.

Коннова Ольга Львовна - главный врач.

614068, Пермь, ул. Екатерининская, д. 224

Olga L. Konnova - Sports Medicine Dispensary.

224, Ekaterininskaya str., Perm, 614068

fizdisp@bk.ruhttps://orcid.org/0000-0003-1820-299XПовароваО. В.PovarovaO. V.

Поварова Оксана Викторовна - к.м.н., старший научный сотрудник кафедры фармакологии МНОИ.

119991, Москва, Ломоносовский проспект, д. 27, корп. 1

Oxana V. Povarova - M.D., Ph.D. (Medicine), Senior Researcher, Department of Pharmacology, Medical Scientific and Educational Institute, M.V. Lomonosov Moscow State University.

1 Leninskiye Gory str., Moscow, 119991

oxpovarova@gmail.comФедеральное государственное бюджетное образовательное учреждение высшего образования «Московский государственный университет имени М.В. Ломоносова»; Научно-исследовательский институт экспериментальной кардиологии имени академика В.Н. Смирнова ФГБУ «Национальный медицинский исследовательский центр кардиологии имени академика Е.И. Чазова» Министерства здравоохранения Российской ФедерацииРоссияLomonosov Moscow State University; Scientific Research Institute of Experimental Cardiology named after Academician V.N. Smirnov, “National Medical Research Centre of Cardiology named after Academician E.I. Chazov”Russian FederationРегиональная физкультурно-спортивная общественная организация «Федерация смешанного боевого единоборства (ММА) Пермского края»РоссияPerm City Federation of Martial ArtsRussian FederationГБУЗ Пермского края «Врачебно-физкультурный диспансер»РоссияSports Medicine DispensaryRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Московский государственный университет имени М.В. Ломоносова»РоссияLomonosov Moscow State UniversityRussian Federation2025171120251522030Copyright © Медведев О.С., Южаков А.А., Коннова О.Л., Поварова О.В., 20252025Медведев О.С., Южаков А.А., Коннова О.Л., Поварова О.В.Medvedev O.S., Uzhakov A.A., Konnova O.L., Povarova O.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.smjournal.ru/jour/article/view/704Цель исследования

Цель исследования: изучение влияния периодических ингаляций молекулярного водорода в течение одного месяца на основные характеристики работоспособности, уровень лактата и другие биохимические показатели, определяемые в крови молодых спортсменов-борцов после физической нагрузки.

Материалы и методы

Материалы и методы. В проспективном клиническом исследовании приняли участие 10 здоровых добровольцев-спортсменов, которым проводился анализ уровня водорода и метана в выдыхаемом воздухе, общеклинический и биохимический анализы крови, оценивались физиологические параметры состояния сердечно-сосудистой системы и основные характеристики работоспособности после физической нагрузки до и после ингаляций молекулярного водорода.

Результаты

Результаты. Ингаляции с молекулярным водородом привели к снижению уровня метана в выдыхаемом воздухе (преимущественно у метанопродуцентов), уменьшению щелочной фосфатазы, увеличению тромбинового времени, активированного частичного тромбопластинового времени, а также снижению уровня лактата до физических нагрузок с увеличением после физических нагрузок. В общеклиническом анализе крови статистически значимых изменений выявлено не было. При проведении тредмил-теста ингаляции молекулярного водорода приводили к снижению диастолического артериального давления на уровне аэробного порога и анаэробного порога с увеличением дыхательного коэффициента. В тесте на гребном тренажере после ингаляций молекулярного водорода было выявлено увеличение дистанции, пройденной за две минуты, а также более быстрое восстановление систолического артериального давления на пятой минуте после окончания нагрузки.

Заключение

Заключение. Полученные данные свидетельствуют о положительном влиянии ингаляций молекулярного водорода на состояние свертывающей системы крови и состояние сердечно-сосудистой системы, что вносит вклад в улучшение показателей работоспособности и выносливости при физической нагрузке у спортсменов.

Purpose of the study

Purpose of the study: to investigate the effect of periodic hydrogen inhalations for one month on the main performance characteristics, lactate levels and other biochemical parameters determined in the blood of young wrestlers after physical activity.

Materials and methods

Materials and methods. 10 healthy volunteer athletes took part in a prospective clinical study. The analysis of hydrogen and methane levels in exhaled air, complete blood count and biochemical blood parameters, physiological parameters of the cardiovascular system, the main performance characteristics after physical activity before and after hydrogen inhalations were carried out.

Results

Results. Hydrogen inhalations led to a decrease in the methane level in the exhaled air mainly of methane producers. A decrease in alkaline phosphatase, an increase in thrombin time, activated partial thromboplastin time, a decrease in lactate levels before exercise with an increase after exercise were noted. No changes were found in the complete blood count. A decrease in diastolic blood pressure at the aerobic threshold and anaerobic threshold with an increase in the respiratory coefficient was noted in the treadmill test. An increase in the distance covered in 2 minutes, as well as a faster recovery of systolic blood pressure at the 5th minute were found in the rowing machine test.

Conclusion

Conclusion. The obtained data indicate a positive effect of hydrogen inhalation on the blood coagulation and cardiovascular system, alkaline phosphatase, which makes an important contribution to improving performance and endurance during physical exercise in athletes.

ингаляции с молекулярным водородомконцентрация водорода и метана в выдыхаемом воздухелактатсвертывающая система кровитредмил-тестгребной тренажерmolecular hydrogen inhalationhydrogen and methane concentration in exhaled airlactateblood coagulation systemtreadmill testrowing machine testАвторы выражают глубокую признательность всем добровольцам — спортсменам Пермского клуба ММА Центр, принявшим участие в данном исследовании. Авторы признательны всем медицинским сотрудникам ГБУЗ ПК «Врачебно-физкультурный диспансер», принявшим активное участие в проведении данного исследования: Сиротину А.Б., Клестову В.В., Гининой Е.В., Журавлевой В.В., Захарову С.Г., Новикову Д.В., Симоненкову С.И., Шиловой С.Н., Капитоновой Л.С.The authors express their deep gratitude to all volunteer athletes of the Perm MMA Center club who took part in this study. 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The authors declare that there are no conflicts of interest present.