smjournalСпортивная медицина: наука и практикаSports medicine: research and practice2223-25242587-9014NEICON10.47529/2223-2524.2025.2.5smjournal-731Research ArticleФИЗИОЛОГИЯ И БИОХИМИЯ СПОРТАSPORTS PHYSIOLOGY AND BIOCHEMISTRYКинетика сердечного тропонина I в ротовой жидкости после забегов на дистанции 5 и 21 кмThe kinetics of cardiac troponin I in saliva following 5-km and 21-km running trialshttps://orcid.org/0000-0001-7527-3503ОвчинниковА. Н.OvchinnikovA. N.

Овчинников Александр Николаевич - доцент кафедры спортивной медицины и психологии.

пр-т Гагарина, 23, Нижний Новгород, 603022

Aleksandr N. Ovchinnikov - Associate Professor, Department of Sports Medicine and Psychology, National Research Lobachevsky State University of Nizhny Novgorod.

23 Gagarin Avenue, Nizhny Novgorod, 603022

alexander_ovchinnikov91@mail.ruФГАОУ ВО «Национальный исследовательский Нижегородский государственный университет им. Н.И. Лобачевского»РоссияNational Research Lobachevsky State University of Nizhny NovgorodRussian Federation2025171120251521219Copyright © Овчинников А.Н., 20252025Овчинников А.Н.Ovchinnikov A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.smjournal.ru/jour/article/view/731Цель исследования

Цель исследования: сравнить изменения концентрации сердечного тропонина I (сТн-I) в слюне у спортсменов после забегов на дистанции 5 и 21 км.

Материалы и методы

Материалы и методы. В исследовании приняли участие 32 спортсмена мужского пола, которые были разделены на две группы. Группа 1 (n = 16) преодолевала дистанцию 5 км, группа 2 (n = 16) — 21 км. Слюна собиралась методом нестимулированного сплевывания до начала забега (Т1), после забега (Т2), через 4 часа (Т3) и 24 часа (T4) после его окончания. Концентрация сТн-I в слюне определялась с использованием анализатора Getein. Полученные данные представлены в виде медианы и межквартильного размаха (Ме [IQR]).

Результаты

Результаты. Уровень сТн-I в слюне значительно увеличился как после забега на дистанцию 5 км, так и после преодоления дистанции 21 км. При этом более высокие пиковые значения сТн-I наблюдались после забега на дистанцию 5 км. Так, уровень сТн-I в слюне был статистически значимо выше в Т2 (группа 1: 0,38 [0,34–0,41] нг/мл; группа 2: 0,33 [0,29–0,35] нг/мл) по сравнению с Т1 (группа 1: 0,14 [0,13–0,16] нг/мл; группа 2: 0,15 [0,13–0,17] нг/мл), достигая максимума в Т3 (группа 1: 0,59 [0,54–0,64] нг/мл; группа 2: 0,40 [0,38–0,44] нг/мл) и возвращаясь к исходному уровню к Т4 (группа 1: 0,17 [0,13–0,20] нг/мл; группа 2: 0,13 [0,11–0,17] нг/мл).

Заключение

Заключение: забег на дистанцию 5 км вызывал более выраженное повышение уровня сТн-I в слюне у спортсменов по сравнению с забегом на дистанцию 21 км, что указывает на доминирующую роль интенсивности аэробной нагрузки в высвобождении сТн-I.

Objective

Objective: to compare changes in salivary concentrations of cardiac troponin I (cTnI) in athletes after 5-km and 21-km running trials.

Materials and methods

Materials and methods: 32 male athletes were recruited and assigned to two groups. Participants of group 1 (n = 16) completed a 5-km running trial, while participants of group 2 (n = 16) completed a 21-km running trial. Unstimulated saliva was collected using the spitting method at pre-exercise (T1), post-exercise (T2), 4 hours post-exercise (T3), and 24 hours post-exercise (T4). Salivary concentrations of cTnI were measured using a Getein analyser. Data are expressed as median and interquartile range (Me [IQR]).

Results

Results: Salivary levels of cTnI increased significantly in both running trials, with higher peak values occurring after the 5-km running trial compared with those of the 21-km running trial. cTnI levels in saliva rose at T2 (group 1: 0.38 [0.34–0.41] ng/mL; group 2: 0.33 [0.29–0.35] ng/mL) compared to T1 (group 1: 0.14 [0.13–0.16] ng/mL; group 2: 0.15 [0.13–0.17] ng/mL), peaked at T3 (group 1: 0.59 [0.54–0.64] ng/mL; group 2: 0.40 [0.38–0.44] ng/mL), and returned to baseline by T4 (group 1: 0.17 [0.13–0.20] ng/mL; group 2: 0.13 [0.11–0.17] ng/mL).

Conclusion

Conclusion: A 5-km running trial induced a greater increase in salivary levels of cTnI in athletes compared to a 21-km running trial, indicating a dominant role of exercise intensity in cTnI release.

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The authors declare that there are no conflicts of interest present.