Modern (rational) methods for detecting genetic features of athletes
https://doi.org/10.47529/2223-2524.2021.4.2
Abstract
Molecular genetic methods are an integral part of recent medicine. Polymerase chain reaction, Sanger sequencing, next-generation sequencing are widely used in many areas: diagnostics of infectious, inherited, oncological diseases, prenatal screening, study of polymorphisms that increase the risk of developing multifactorial diseases or promoting development physical qualities necessary to achieve success in sports and competitive activity. The growing demand for genotyping raises a number of ethical and social issues affecting the degree of usefulness of genotyping a healthy person and the scientific reliability of the data obtained using direct-to-consumer genetic testing.
The review presents and systematizes the laboratory diagnostic methods used today to study nucleic acids that carry important information about human health and physical qualities.
About the Authors
A. V. Zholinsky
Federal Scientific and Clinical Center for Sports Medicine and Rehabilitation of the FMBA of Russia
Russian Federation
Russian Federation
Anastasia I. Kadykova, doctor of clinical laboratory diagnostics
5, Bolshaya Dorogomilovskaya str., Moscow, 121059, Russia
+7 (960) 878-26-17
A. I. Kadykova
Federal Scientific and Clinical Center for Sports Medicine and Rehabilitation of the FMBA of Russia
Russian Federation
Russian Federation
Anastasia I. Kadykova, doctor of clinical laboratory diagnostics
5, Bolshaya Dorogomilovskaya str., Moscow, 121059, Russia
+7 (960) 878-26-17
V. S. Feshchenko
Federal Scientific and Clinical Center for Sports Medicine and Rehabilitation of the FMBA of Russia; Pirogov Russian National Research Medical University (Pirogov Medical University)
Russian Federation
Russian Federation
Vladimir S. Feshchenko, M.D., Ph.D. (Medicine), Head of the Organizational-Research Department; Assistant Professor of the Department of Rehabilitation, Sports Medicine and Physical Education
5, Bolshaya Dorogomilovskaya str., Moscow, 121059, Russia
5, bld. 2, Ostrovityanova str., Moscow, 117997, Russia
+7 (499) 795-68-53
M. G. Hovhannisyan
Federal Scientific and Clinical Center for Sports Medicine and Rehabilitation of the FMBA of Russia
Russian Federation
Russian Federation
Mkrtych G. Hovhannisyan, M.D., Ph.D. (Biology), Head of the Organizational-Research Department
5, Bolshaya Dorogomilovskaya str., Moscow, 121059, Russia
+7 (499) 795-68-53
A. V. Zorenko
Federal Scientific and Clinical Center for Sports Medicine and Rehabilitation of the FMBA of Russia
Russian Federation
Russian Federation
Anna V. Zorenko, sports medicine physician of the Federal Research and Medical Center
5, Bolshaya Dorogomilovskaya str., Moscow, 121059
+7 (499) 795-68-53
R. V. Deev
Federal Scientific and Clinical Center for Sports Medicine and Rehabilitation of the FMBA of Russia; I.I. Mechnikov North-Western State Medical University
Russian Federation
Russian Federation
Roman V. Deev, M.D., Ph.D. (Medicine), lead researcher; Head of the Departament of Pathological Anatomy
5, Bolshaya Dorogomilovskaya str., Moscow, 121059, Russia
41 Kirochnaya str., St. Petersburg 191015, Russia
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For citations:
Zholinsky A.V., Kadykova A.I., Feshchenko V.S., Hovhannisyan M.G., Zorenko A.V., Deev R.V. Modern (rational) methods for detecting genetic features of athletes. Sports medicine: research and practice. 2021;11(4):5-16. (In Russ.) https://doi.org/10.47529/2223-2524.2021.4.2
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