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The problem of the course reception of sympatomimetics from the group of aliphatic amines safety (geranamine, octodrine, AMP citrate)

https://doi.org/10.47529/2223-2524.2021.4.7

Abstract

Sport nutrition used to reduce weight or improve performance may contain psychostimulant aliphatic amines. The most common of them are DMAA, octodrine and AMP citrate. There are no toxicometric data for above compounds, which prevents their preclinical and clinical study and the formation of optimal dosing regimens or algorithms for overdose therapy. We determined that all of the above drugs have a low degree of cumulation of <20%. Based on the properties of this class of drug, the course should not exceed 7 days in order to avoid complications and the development of addiction.

About the Authors

O. A. Yakovlev
State Scientific Research Test Institute of the Military Medicine
Russian Federation

Oleg A. Yakovlev, researcher

4, Lesoparkovaya str., St. Petersburg, 195043, Russia



M. S. Vakhviyaynen
State Scientific Research Test Institute of the Military Medicine
Russian Federation

Mariya S. Vakhviyaynen, junior researcher

4, Lesoparkovaya str., St. Petersburg, 195043, Russia



M. A. Judin
State Scientific Research Test Institute of the Military Medicine
Russian Federation

Mihail A. Judin, Ph.D. (Medicine), Associate Professor

4, Lesoparkovaya str., St. Petersburg, 195043, Russia



A. G. Anokhin
State Scientific Research Test Institute of the Military Medicine
Russian Federation

Aleksandr G. Anokhin, M.D., Ph.D. (Medicine)

4, Lesoparkovaya str., St. Petersburg, 195043, Russia



A. V. Konovalov
State Scientific Research Test Institute of the Military Medicine
Russian Federation

Aleksei V. Konovalov, researcher

4, Lesoparkovaya str., St. Petersburg, 195043, Russia



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Review

For citations:


Yakovlev O.A., Vakhviyaynen M.S., Judin M.A., Anokhin A.G., Konovalov A.V. The problem of the course reception of sympatomimetics from the group of aliphatic amines safety (geranamine, octodrine, AMP citrate). Sports medicine: research and practice. 2021;11(4):69-77. (In Russ.) https://doi.org/10.47529/2223-2524.2021.4.7

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ISSN 2223-2524 (Print)
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