Resistance training significantly increases insulin-like growth factor-1 levels in women with a sedentary lifestyle: A randomized controlled trial
https://doi.org/10.47529/2223-2524.2025.3.7
Abstract
Purpose of the study: To determine the effects of physical exercise resistance training and aerobic exercise on Insulin-Like Growth Factor-1 (IGF-1) levels in women with a sedentary lifestyle.
Methods: Thirty-three female respondents with sedentary lifestyle were randomly selected and divided into three groups: resistance training group (n = 11), aerobic training group (n = 11), and control group (n = 11). Study participants were between 18 and 26 years old. Data collection took place over the course of two days, beginning with the collection of information regarding the characteristics of the subjects. Before the exercise, the subjects had their blood drawn as pre-test data. The subjects were then instructed to warm up. Then, the subjects performed physical exercises according to their group. After the exercise intervention, blood samples were taken as post-test data.
Results: The data showed that training significantly increased IGF-1 levels in resistance training group (p = 0.012).
Conclusion: acute resistance exercise has the potential to raise IGF-1 levels. Growth hormone’s effects are mediated by IGF-1, which is also essential for controlling somatic growth and organ development, including brain. Resistance training can be recommended as an alternative exercise for people with a sedentary lifestyle to improve cognitive function.
Supporting agencies: The Republic of Indonesia’s Ministry of Higher Education, Science, and Technology provided financial assistance for this study under contract number 128/C3/DT.05.00/PL/2025.
About the Authors
N. Ayubi
Universitas Negeri Surabaya
Indonesia
Indonesia
Ayubi Novadri, Dr., Lecturer and Researcher, Department of Physical Education, Health and Recreation, Universitas Negeri Surabaya, Jl. Lidah Wetan, Jawa Timur, Surabaya, 60213, Indonesia.
J. C. Wibawa
STKIP PGRI Trenggalek
Indonesia
Indonesia
Wibawa Junian Cahyanto, M.Kes., Lecturer, Department of Physical Education, Health and Recreation, STKIP PGRI Trenggalek, Jl. Supriyadi str., 22, Trenggalek, Jawa Timur, 66319, Indonesia.
V. M. Sceisarriya
STKIP PGRI Trenggalek
Indonesia
Indonesia
Vega Mareta Sceisarriya, M.Ed., Lecturer, Department of Physical Education, Health and Recreation, STKIP PGRI Trenggalek, Jl. Supriyadi str., 22, Trenggalek, Jawa Timur, 66319, Indonesia.
P. B. Dafun Jr.
Mariano Marcos State University
Philippines
Philippines
Procopio B. Dafun Jr., M.Ed., Lecturer, Department of Physical Education, Mariano Marcos State University Quiling str., 16, Batac, Ilocos Norte, 2906, Philippines.
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For citations:
Ayubi N., Wibawa J.C., Sceisarriya V.M., Dafun Jr. P.B. Resistance training significantly increases insulin-like growth factor-1 levels in women with a sedentary lifestyle: A randomized controlled trial. Sports medicine: research and practice. 2025;15(3):34-43. https://doi.org/10.47529/2223-2524.2025.3.7
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